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Intra Cytoplasmic Sperm Injection (ICSI) is the latest and, to date, the most successful micromanipulation technique used for the treatment of male factor infertility. The procedure entails the mechanical insertion of a single spermatozoon directly into the cytoplasm of an oocyte. ICSI fertilization was reported in 1988 using human gametes, however, there were no reports of pregnancies until July 1992 (Palermo et al. 1992). Since then, there have been ICSI pregnancy rates comparable to conventional In Vitro Fertilization (IVF).

This technique is now employed for patients with

Severe male factor infertility like Azoospermia or Severe Oligospermia
Severe endometriosis,
Polycystic ovarian diseases not responding to conventional treatments.
Unexplained infertility
Previous failed IVFs.

Pregnancy Rate

40-70%


 
   
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