Intra Cytoplasmic Sperm Injection (ICSI) is the
latest and, to date, the most successful micromanipulation
technique used for the treatment of male factor
infertility. The procedure entails the mechanical
insertion of a single spermatozoon directly into
the cytoplasm of an oocyte. ICSI fertilization was
reported in 1988 using human gametes, however, there
were no reports of pregnancies until July 1992 (Palermo
et al. 1992). Since then, there have been ICSI pregnancy
rates comparable to conventional In Vitro Fertilization
(IVF).
This technique
is now employed for patients with
Severe
male factor infertility like Azoospermia or
Severe Oligospermia
Severe endometriosis,
Polycystic ovarian
diseases not responding to conventional treatments.